How Simulation Analysis in Biology and Virtual Labs are Shaping Science Education

Last Updated on December 26, 2024 by Nourhan Essam

Simulation analysis in biology involves the use of computer simulations of biological systems to analyze and visualize complex cellular processes.

The biological systems include the networks of metabolites and enzymes which comprise metabolism, signal transduction pathways, gene regulatory networks, and more.

In this blog post, we will explore simulation analysis in biology, its role, how computational biology is shaping our understanding of living systems, how simulation analysis transforms biological research. Additionally we will dive into PraxiLabs’ Virtual Biology simulations.

Explanation of Simulation-based Models (Simulation Analysis in Biology) and Their Role

There are many applications of Simulation- based models and techniques in the biological field. for examples:

  •       Molecular and chemical levels of biological simulations are classified to bio-molecular simulation, whichdeal with the dynamics of molecular, DNA, RNA, Protein and neuron cells.
  •       Metabolic system levels of biological simulations are grouped as metabolic simulation.
  •   Simulations of systems such as the circulatory, respiratory, tissue and muscle, immune, and brain systems are included in Metabolic Simulation.
  •       Population Simulation, Modeling & Simulation in Epidemiology and Agricultural System Simulation are included in Ecosystem Simulation.

thus,we can say that Modeling & Simulation techniques have applications in medical, pharmaceutical studies. They are also used for epidemiological, agricultural and educational purposes also.

Modeling and Simulation techniques are important tools to conduct research for biologists. It makes biologists understand more complex processes in biological systems which were not possible to explain with mathematical biological systems.

Modeling and simulation techniques are important tools for conducting research in biology. They enable biologists to understand complex processes in biological systems that were previously difficult to explain using traditional mathematical models.

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Exploring Biological Systems Through Computational Models

With computational models playing an ever increasing role in the advancement of science, it is important that researchers understand what it means to model something, recognize the implications of the conceptual, mathematical and algorithmic involved in model construction; and comprehend what models can and cannot do.

Models can serve a wide variety of roles, including hypothesis testing, generating new insights, deepening understanding, suggesting and interpreting experiments, tracing chains of causation, doing sensitivity analyses, integrating knowledge, and inspiring new approaches.

 Models can bring together varied types of information and do so across a range of length scales, as they do in multi-scale, multifaceted embryogenesis models. some of which connect gene expression, the cytoskeleton, cell properties, tissue mechanics, morphogenetic movements and phenotypes.

Models cannot replace experiments nor can they prove that particular mechanisms are at work in a given situation. But they can demonstrate whether or not a proposed mechanism is sufficient to produce an observed phenomenon.

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The Role of Virtual Labs in Biological Research

Virtual laboratories encourage e-learning  through  online protocols, simulations, animation videos, video-tutorials, self- evaluation designed for each objective and experiments in any area of science and technology.

Remote access to instruments has further enhanced the utility of virtual laboratories and forms a strong laboratory component.

Virtual Laboratory often includes tools for data analysis that can help both the students and teachers by helping them to collect, analyze, and interpret data generated from 3D virtual experiments. This works to increase their learning outcomes and also teaches them important techniques for data analysis.

Also, the visualization sources like lab manuals, walkthrough videos, tutorials, and more help strongly in this point.

In real laboratories in colleges and universities, dangerous experiments are often canceled and only studied theoretically to ensure the safety of students.

Virtual Laboratories offer a very safe environment, enabling students to conduct dangerous experiments in a risk-free environment.  They can do and understand complex experiments without the worry of dealing with harmful chemicals or any other hazards.

PraxiLabs, the 3D virtual lab solution, provides students with access to realistic biology, chemistry, and physics labs and enriches their understanding with a variety of informational and educational content.. Choose the best plan for you now!

Study | Investigating the effect of virtual laboratories on students’ academic performance and attitudes towards learning biology

This  research aimed to delve into the impact of virtual laboratories on students’ attitudes toward biology and their performance in biology topics perceived as difficult. The research involved 168 Rwandan upper secondary school students and employed survey research combined with a quasi-experimental research design. The control group comprised 83 students and was taught with the conventional teaching method, while the experimental group comprised 85 and was treated under technology-based  instruction using virtual laboratories.

Furthermore, a focus  group  interview  was  used  to  get  qualitative  data  about attitudinal changes before and after the intervention. Concepts of nerve cells and identification of food nutrients, and enzyme activities were the focus of this study.

 The results indicated an important effect of an intervention to improve students’ attitudes toward the learned topics (p value < 0.05) and performance in favor of the experimental group. The focus group interviews revealed that prior to teaching interventions, nerve cells topic was abstract and daunting to students and the visualization exercises helped them to understand while increasing their interest and engagement.

 The study recommends the use of virtual lab to realistic biology for teaching difficult and abstract concepts to encourage positive attitudes toward learning biology.

PraxiLabs Virtual Biology Adventures: Discover, Learn, and Experiment

Explore the Extraordinary: Exciting Examples of 3D Science Experiments

PraxiLabs is the 3D interactive virtual lab solution provides students with access to realistic biology, chemistry, and physics labs and enriches their understanding with a variety of informational and educational content designed to enhance their understanding and learning, with the aim of providing equal opportunity for an enhanced STEM education for students everywhere.

 All you need to start our virtual biology lab simulations is: 

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No hardware setup. No credit card required. Get started in seconds

Choose from 200+ Simulations

Select 3 FREE Simulations and get started 

Practice as Many Times as You Want

Your lab partner will help you out, plus you’ll have access to walkthrough videos, tutorials, & more

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We provide a diverse catalog of choices, students can now practice the same virtual biology practical simulation for an unlimited number of times, with 0% risk and 100% supervision, in biology and its sub-disciplines:

Molecular Biology Experiments

Here are some examples of the virtual lab experiments available:

  •       DNA Extraction 
  •       Conventional PCR             
  •       Agarose Gel Electrophoresis of DNA          
  •       Real Time PCR  
  •       RNA Extraction                   
  •       cDNA Synthesis
  •       DNA Sequencing                                       
  •       DNA Microarray                 
  •       Western Blot
  •       2D Protein Electrophoresis (Isoelectric Point Focusing, PAGE)                                                                                                              
  •       Protein Electrophoresis (Polyacrylamide Gel Electrophoresis-PAGE)
  •       Cloning-DNA Isolation and Restriction Digestion                  
  •       Cloning – Transformation                                                                                                                                               
  •       Cloning-Blue and White Screening                                                                                                                          
  •       Cloning-Growth and Isolation of Plasmid DNA using Alkaline Lysis Method      
  •       Cloning-DNA Agarose Gel Electrophoresis of Digested Plasmid and Selection for Sequencing                                                

Microbiology Lab Experiments

Here are some examples of the virtual lab experiments available:

  •       Gram Stain                                                                                                                                       
  •       Ziehl-Neelsen Staining Technique              
  •       Cultivation and Preparation of the Virus in Chick Embryo
  •       Preparation of Washed Red Blood Cells                                                                                   
  •       Haemagglutination Tests                                                                                                             
  •       Bacterial Plating Out Technique Experiment (Streak plate method)
  •       Catalase Test
  •       Oxidase Test  
  •       Coagulase Test                                                                                                                                   
  •       Antibiotic Sensitivity Test (Disc Diffusion Method)
  •       Indole Test           
  •       Spread Plate Technique  
  •       Urease Test          
  •       Widal Test

 Pharmacology Experiments

Here are some examples of the virtual lab experiments available:

  •       Adherent Cell Culturing using Mammalian Cell Lines
  •       In Vitro Viability Assay Using Tetrazolium Salt XTT
  •       In Vitro Cell Viability by the Lactate Dehydrogenase Assay (LDH)
  •       In Vitro Cell Viability by the Alamar Blue Assay
  •       In Vitro Histone H2AX Phosphorylation Assay
  •       In Vitro 8-Hydroxydeoxy Guanosine (8-OHdG) Assay
  •       In Vitro Bromodeoxyuridin (BrdU) Assay
  •       Annexin V Assay 
  •       In Vitro Mammalian Cells COMET Assay
  •       In Vitro Cytokinesis-Block Micronucleus Assay 
  •       In-Vitro Chromosomal Aberrations Test 
  •       In Vitro Caspase 3 Activity Assay 
  •       In Vitro Fluorescein Diacetate/Propidium Iodide (FDA/PI) Staining Assay 
  •       In Vitro Neutral Red Uptake Assay 
  •       In Vitro Acid Phosphatase Assay for Cell Viability 

Biochemistry Lab Experiments

 Here are some examples of the virtual lab experiments available: 

  •       Total Protein Estimation (Bradford)           
  •       High Performance Liquid Chromatography- Protein (HPLC) 
  •       Building a Model for Catalytic Interactions             
  •       Polarographic Oxygen Respirometry (Bioenergetics)  

Immunology Lab Experiments

Here are some examples of the virtual lab experiments available:

  •       Elispot assay (Dot ELISA)                
  •       Flow Cytometry – Cell Cycle           
  •       Immunofluresence Assay
  •       Production of Monoclonal Antibodies (mAB)-Hybridomas Technique  

Physiology Virtual Experiments            

Our virtual lab experiments in physiology can cover a wide range of topics, including:

  •       Red Blood Cell Count
  •       Amylase test  

Safety Laboratory

Learn all safety instructions and precautions,including safety signs, material safety, data sheets, and more in our safety lab simulation.

 Talk to our experts and elevate your students’ Learning Retention and Engagement with PraxiLabs’ Biology virtual labs!

About Nourhan Essam

Nourhan Essam is a Senior Content Writer at PraxiLabs, with a deep passion for crafting impactful scientific content. With over 6 years of experience, she has developed robust expertise in e-learning, education, science, and digital marketing. Nourhan leverages her comprehensive understanding to produce high-quality, compelling, and informative pieces in both Arabic and English. Dedicated to enhancing the quality of scientific content, she ensures that each piece is engaging, educational, and aligned with the needs of her audience.